Publications by authors named "M Sbai Idrissi"
Impact of deep neuromuscular blockade on intraoperative NOL-guided remifentanil requirement during desflurane anesthesia in laparoscopic colorectal surgeries: A randomised controlled trial.
J Clin Anesth
December 2024
Article Synopsis
- The study aimed to assess how deep neuromuscular blockade (NMB) affects pain and opioid use during laparoscopic colorectal surgery compared to moderate NMB.
- 100 patients were randomly divided into deep and moderate NMB groups, with the deep group requiring significantly less remifentanil (an opioid) during surgery.
- Results indicated that deep NMB improved surgical conditions, evidenced by a better Leiden Surgical Rating Scale and lower intra-abdominal pressure, while postoperative pain and analgesic use were similar to the moderate group.
Background: This study investigated the safety, reactogenicity, and immunogenicity in healthy subjects of a Clostridioides difficile vaccine candidate with/without adjuvant, targeting toxins A and B.
Methods: In this first-in-human, phase 1, observer-blind study, subjects aged 18-45 years were randomized to receive F2 antigen (n = 10) or placebo (n = 10), and subjects aged 50-70 years to receive F2 antigen plus AS01 adjuvant (n = 45), F2 antigen (n = 45), or placebo (n = 30) in 2 doses 1 month apart. A subcohort (n = 40) received a third dose 15 months later.
sp. nov., efficient nodulating rhizobia isolated from roots in Tunisia.
Int J Syst Evol Microbiol
September 2024
Article Synopsis
- Researchers characterized three bacterial strains (1AS14I, 1AS12I, and 6AS6) from root nodules using various analytical techniques, revealing they belong to a distinct lineage within the rhizobia complex.
- Phylogenetic analysis showed that these strains are closely related to a known species but maintain a sequence identity of only 96.4%, indicating they are not the same species.
- The study proposes naming the new species as
- [insert proposed name]
- sp. nov., with strain 1AS14I as the type strain, enhancing our understanding of microbial diversity in nitrogen-fixing ecosystems in Tunisia.
Article Synopsis
- Scientists wanted to find out if propofol is better than sevoflurane at reducing pain during surgery.
- They studied 60 adult patients who were having laparoscopic surgery and used either propofol or sevoflurane to put them to sleep.
- The results showed that both anesthetics were about the same at blocking pain, but sevoflurane had a slightly better effect after a specific pain test.
Introduction: There is a sizable niche for a minimally invasive analgesic technique that could facilitate ambulatory video-assisted thoracoscopic surgery (VATS). Our study aimed to determine the analgesic potential of a single-shot erector spinae plane (ESP) block for VATS. The primary objective was the total hydromorphone consumption with patient-controlled analgesia (PCA) 24 h after surgery.
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