Publications by authors named "M Sayki"
Background: Heart type fatty acid binding protein (H-FABP) is a small protein and released into the circulation when myocardial damage has occurred. Previous studies have demonstrated that H-FABP is closely associated with cardiac and some endocrinologic disorders including prediabetes, metabolic syndrome, and acromegaly. Hyperthyroism is a well-known disorder associated with cardiovascular diseases.
View Article and Find Full Text PDFBackground: There is growing consensus in the literature that inflammation plays a central role in the pathophysiology of obesity and type 2 diabetes mellitus (T2DM) and cardiovascular complications. Neutrophil-to-lymphocyte ratio (NLR) provides a simple method for assessment of inflammatory status and it is a new, inexpensive marker. The aim of the present study was to investigate the predictive value of preprocedural (before the OGTT) NLR on development of type 2 diabetes (T2DM) in morbid obesity patients (MOP).
View Article and Find Full Text PDFBackground: Nonalcoholic fatty liver disease (NAFLD) is an emerging problem all over the world. Because NAFLD and polycystic ovary syndrome (PCOS) are both closely related with insulin resistance, it would be necessary to determine the rate of presence of NAFLD in PCOS patients. So, this study aimed to investigate the utility of M30 in PCOS patients for the diagnosis of hepatic injury.
View Article and Find Full Text PDFPotential proteomic biomarkers in assessing liver fibrosis using SELDI-TOF MS.
Turk J Gastroenterol
February 2012
Article Synopsis
- This study aimed to find proteomic biomarkers to assess liver fibrosis severity in patients with chronic liver disease, which is crucial for treatment decisions and prognosis.
- The analysis involved serum samples from 83 patients and 29 healthy controls, using advanced mass spectrometry to identify differences in protein profiles linked to fibrosis stages.
- Findings showed over 30 protein peaks distinguishing cirrhotic patients from those with less severe fibrosis, with specific markers enabling accurate differentiation between mild and advanced disease stages.*
Background: Early atherosclerosis and increased risk of cardiovascular diseases (CVD) have been reported in patients with polycystic ovary syndrome (PCOS). Oxidative stress is an accepted risk factor for the development of CVD.
Aim: To evaluate the association between oxidative stress markers [ischemia-modified albumin (IMA), total antioxidant status (TAS), and total oxidant status (TOS) levels], carotid intima- media thickness (CIMT), endocrine and metabolic parameters in patients with PCOS.