Publications by authors named "M Sayarlioglu"
Background: Familial Mediterranean fever (FMF) is an autosomal recessive genetic disease. Amyloidosis is the most important complication of FMF that determines the prognosis of the disease.
Aims: In our study, we have investigated the relationship between the genetic mutations with the disease severity and the frequency of development of amyloidosis inpatients with FMF.
Article Synopsis
- The study aimed to evaluate how anti-TNF treatment affects work productivity, activity impairment, quality of life (QoL), and disease activity in patients with psoriatic arthritis (PsA).
- A total of 120 patients were monitored over 9 months, using questionnaires and scores to assess improvements in their condition and functioning.
- Results showed significant reductions in activity impairment and disease activity, with a notable percentage of patients achieving clinical response criteria by the end of the study, indicating effective treatment outcomes.
Objective: To compare the clinical features, laboratory findings, and prognosis of Behçet's disease (BD) patients with and without Budd-Chiari syndrome (BCS).
Methods: This multicenter retrospective study investigated 61 (M/F: 41/20) patients with BD, having coexistent BCS, and 169 (M/F:100/69) BD patients as the control group without BCS from 22 different centers of Turkey diagnosed between 1990 and 2017.
Results: Of the total 61 BD patients with BCS, the onset of the first symptom and the median age of diagnosis were earlier in contrast to BD patients without BCS (p = 0.
Background/aim: The distribution of Mediterranean fever (MEFV) gene mutations in Turkish familial Mediterranean fever (FMF) patients varies according to geographic area of Turkey. There is a need for highly representative data for Turkish FMF patients. The aim of our study was to investigate the distribution of the common MEFV mutations in Turkish FMF patients in a nationwide, multicenter study.
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- The study looked at Familial Mediterranean fever (FMF), which is a disease where the body has improper inflammation, and focused on mutations in a specific part of the gene called exons.
- Researchers checked data from over 2,200 FMF patients to see how different mutations affected their health.
- They found that patients with mutations in exon 10 had worse symptoms than those with mutations in exon 2, meaning exon 10 mutations are associated with more severe cases of FMF.