Publications by authors named "M Savini"
Healthy mitochondria are critical for reproduction. During aging, both reproductive fitness and mitochondrial homeostasis decline. Mitochondrial metabolism and dynamics are key factors in supporting mitochondrial homeostasis.
View Article and Find Full Text PDFSeizure frequency in treatment-resistant epilepsies seems to be decreased by cannabidiol (CBD), but contrasting data are available on its effect on sleep, behavior, and quality of life (QoL), and no data is reported on its effect on parental stress in patients with epilepsy (PWE). Thus, we conducted a retrospective study on a cohort of children and adults with drug-resistant epilepsy (DRE) who had been treated with highly purified, pharmaceutical-grade CBD to evaluate its effects on seizure frequency, QoL, behavior, parental stress, and sleep. Eighteen patients (12 adults and 6 children) were included in the cohort and followed for a median of 9 months.
View Article and Find Full Text PDFArticle Synopsis
- Dietary mono-unsaturated fatty acids (MUFAs) are associated with increased lifespan in various species, with their mechanisms still being explored.
- Research shows that the number of lipid droplets and peroxisomes plays a key role in MUFA-induced longevity in the organism C. elegans.
- Findings indicate that MUFAs promote lipid droplet and peroxisome growth, which is crucial for longevity and suggests potential pathways for interventions to slow aging.
Healthy mitochondria are critical for reproduction. During aging, both reproductive fitness and mitochondrial homeostasis decline. Mitochondrial metabolism and dynamics are key factors in supporting mitochondrial homeostasis.
View Article and Find Full Text PDF