Publications by authors named "M Sassek"
Article Synopsis
- Osteoporosis in menopausal women may benefit from dietary alternatives like probiotics and isoflavones due to side effects of current medications.
- In a study with post-menopausal osteoporotic rats, combining probiotics and isoflavone (daidzein and tempeh) showed positive effects on bone metabolism and histopathology, despite reduced calcium transporter expression.
- However, using probiotics alone did not significantly improve bone health, indicating that the combination approach is more effective and suggesting further investigation into these dietary interactions is needed.
The aim of this study is to determine the influence of the mitochondrial open-reading-frame of the twelve S rRNA-c (MOTS-c) peptide on pancreatic cell physiology. Moreover, in this study, we examined the changes in MOTS-c secretion and expression under different conditions. Our experiments were conducted using laboratory cell line cultures, specifically the INS-1E and αTC-1 cell lines, which represent β and α pancreatic cells, respectively.
View Article and Find Full Text PDFGIP_HUMAN [22-51] is a recently discovered peptide that shares the same precursor molecule with glucose-dependent insulinotropic polypeptide (GIP). In vivo, chronic infusion of GIP_HUMAN [22-51] in ApoE-/- mice enhanced the development of aortic atherosclerotic lesions and upregulated inflammatory and proatherogenic proteins. In the present study, we evaluate the effects of GIP_HUMAN [22-51] on insulin mRNA expression and secretion in insulin-producing INS-1E cells and isolated rat pancreatic islets.
View Article and Find Full Text PDFOstarine does not enhance the metabolic effect of exercise in obese rats.
J Physiol Pharmacol
August 2023
Overweight and obesity are associated with severe metabolic disorders and an increased risk of cardiovascular diseases. It is a known fact that physical activity has a positive effect on metabolic parameters, and also reduces the risk of diseases such as diabetes. Some products can enhance the rate of lipolysis and help in improving fat loss.
View Article and Find Full Text PDFArticle Synopsis
- The text mentions that it serves as a correction for the article identified by the DOI 10.1016/j.heliyon.2023.e16801.
- It implies that there were errors or inaccuracies in the original publication that needed to be addressed.
- The correction is important for ensuring the integrity and reliability of the scientific information presented in the article.