Publications by authors named "M Sarti"
The present article presents a case report and literature review concerning the subspecies (SEZ), a rare zoonotic pathogen in humans. The case involves a 62-year-old man with no prior heart disease, presenting with endocarditis, pneumonia, and meningitis following close contact with a horse. The patient underwent urgent aortic valve replacement due to severe valvular damage caused by the infection.
View Article and Find Full Text PDFObjective: We investigated the performance of enzyme linked immunospot (ELISpot) assay for the diagnosis of invasive aspergillosis (IA) in high-risk patients with hematologic malignancies.
Methods: We prospectively enrolled two cohorts of patients undergoing intensive myelosuppressive or immunosuppressive treatments at high risk for IA. ELISpot was performed to detect Aspergillus-specific T cells producing Interleukin-10.
Severe acute respiratory syndrome coronavirus 2 infection in patients with hematological malignancies in the Omicron era: Respiratory failure, need for mechanical ventilation and mortality in seronegative and seropositive patients.
EJHaem
June 2024
Article Synopsis
- Patients with hematological malignancies are at a higher risk for severe COVID-19 during the Omicron variant's prevalence, with significant health impacts observed in those with negative SARS-CoV2 serology.
- A study of 112 patients revealed that seronegative individuals were older, more likely to have certain types of cancer, and faced worse health outcomes, including higher rates of respiratory failure, mechanical ventilation, and COVID-related death.
- The findings suggest that negative SARS-CoV2 serology can serve as a useful indicator to identify patients at increased risk for severe complications from COVID-19, highlighting the importance of serology testing in managing these patients.
Background: Intravenous drug users (IDUs) have a high risk of developing skin and soft tissue infections such as erysipelas, abscesses, and less frequently necrotizing fasciitis (NF) or gas gangrene. Rarely, the cause of the infection is microorganisms residing in the oral cavity and can lead to life-threatening infections.
Methods: We describe the case of a 43-year-old man intravenous drug user (IDU) who was admitted for intense leg pain following an injection of cocaine at that site.
Article Synopsis
- - The study investigated Campylobacter infections in Italy from 2017 to 2021, analyzing data from 19 hospitals across 13 regions to understand the epidemiology and antibiotic resistance patterns.
- - A total of 5,419 Campylobacter isolates were analyzed, with C. jejuni being the most prevalent species, and the majority of infections were found in males and outpatients; resistance to common antibiotics like ciprofloxacin and tetracyclines was notably high but showed a decrease over the study period.
- - The findings indicate that while resistance to fluoroquinolones and tetracyclines is decreasing, it remains significant, whereas macrolides show consistent effectiveness against Campylobacter in Italy.