Calotropis procera latex protein reduces inflammation and bone loss in ligature-induced period ontitis in male rats.

Objective: Calotropis procera latex protein (CpLP) is a popular anti-inflammatory and therefore we aimed to study its effects on inflammatory bone loss.

Design: Male Wistar rats were subjected to a ligature of molars. Groups of rats received intraperitoneally CpLP (0.

Effect of a continuous mechanical polishing protocol and toothbrushing on the surface roughness of acrylic resin teeth.

Purpose: To evaluate in vitro the effect of a continuous mechanical polishing protocol, performed in different periods, on the surface roughness of acrylic resin teeth subjected to toothbrushing (Br).

Methods: Artificial acrylic teeth (n=30) were randomly divided into three groups according to the polishing protocol and toothbrushing (Br): Br; Br+Pol15 (Br associated with a biweekly polishing); Br+Pol30 (monthly polishing). Br group was subjected to a total of 89,000 brushing cycles.

The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo.

Drosophila ISWI, a highly conserved member of the SWI2/SNF2 family of ATPases, is the catalytic subunit of three chromatin-remodeling complexes: NURF, CHRAC, and ACF. To clarify the biological functions of ISWI, we generated and characterized null and dominant-negative ISWI mutations. We found that ISWI mutations affect both cell viability and gene expression during Drosophila development.

The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes.

The trithorax group gene brahma (brm) encodes an activator of Drosophila homeotic genes that functions as the ATPase subunit of a large protein complex. To determine if BRM physically interacts with other trithorax group proteins, we purified the BRM complex from Drosophila embryos and analyzed its subunit composition. The BRM complex contains at least seven major polypeptides.

Genetic analysis of brahma: the Drosophila homolog of the yeast chromatin remodeling factor SWI2/SNF2.

The Drosophila brahma (brm) gene encodes an activator of homeotic genes related to the yeast chromatin remodeling factor SWI2/SNF2. Here, we report the phenotype of null and dominant-negative brm mutations. Using mosaic analysis, we found that the complete loss of brm function decreases cell viability and causes defects in the peripheral nervous system of the adult.