Efficacy and Safety of Recombinant Human Prourokinase in Acute Ischemic Stroke Within 4.5 h: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Background: Acute ischemic stroke (AIS) requires timely thrombolysis to restore perfusion and minimize neurological damage. Recombinant human prourokinase (rhPro-UK) has emerged as a promising alternative to alteplase, with potential efficacy and safety benefits within the critical 4.5-h treatment window.

A DFT study of monolayer magnesium carbide (MgC) as a potential anode for (Li, Na, K) alkali metal-ion batteries.

Magnesium carbide (MgC) is the latest two-dimensional monolayer material with semiconductor properties containing 0.25 eV band gap. Upon adsorption of the Li/Na/K the semiconducting behavior of material changes to metallic.

AP2 transcription factor CsAIL6 negatively regulates citric acid accumulation in citrus fruits by interacting with a WD40 protein CsAN11.

Citric acid accumulation is an essential process in citrus fruits that determines fruit flavor and marketability. The MBW complex transcription factor genes, , , and play key roles in regulating citric acid accumulation. Although how to regulate or was widely investigated, studies on the regulation of are scarce.

Metallurgical and Mechanical Properties of Stellite 6 Deposition Developed Through Friction Surfacing Technique.

Friction surfacing (FS) is a solid-state process for depositing metallurgically bonded coatings for corrosion and wear protection. It is particularly attractive for depositing coatings in materials that are difficult to fusion deposit. Stellite 6 is one such material, which is widely used as a protective coating on steel structures to combat wear and corrosion.

Digital Toxicology Teleconsultation for Adult Poisoning Cases in Saudi Hospitals: A Nationwide Study.

: Poisoning represents a significant global public health challenge, particularly with its complex manifestations in adult populations. Understanding regional epidemiology through digital health systems is crucial for developing evidence-based prevention and management strategies. This nationwide study analyzes hospital-based toxicology teleconsultation data from the Toxicology Consultation Service-Saudi Medical Appointments and Referrals Center (TCS-SMARC) platform to characterize the epidemiological patterns, clinical features, and outcomes of adult poisoning cases across Saudi regions.