Publications by authors named "M Sargento Mendes"

Objective: Reduced functional capacity and muscle weakness are two major contributors to functional impairment in chronic obstructive pulmonary disease (COPD). The underlying causes of functional impairment are poorly understood and, therefore, we sought to investigate the contribution of genetic factors.

Methods: We conducted a cross-sectional analysis of sociodemographic, clinical and genetic information of people with COPD.

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Cardiovascular diseases are the leading cause of death globally and in Brazil. The provision of quality healthcare faces challenges due to resource scarcity and unequal distribution, particularly affecting rural areas. Telehealth strategies have shown potential to address these challenges by improving access to specialised care.

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Topic Importance: Education and psychosocial support are essential components of pulmonary rehabilitation (PR). However, the delivery of education often follows a one-size-fits-all approach, with individual factors that influence learning rarely considered. Moreover, education-related outcomes are frequently overlooked in PR assessments, and inconsistent use of these outcomes has limited our understanding of the impact of education on people with chronic respiratory diseases.

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Article Synopsis
  • Organ-on-a-chip systems (or microphysiological systems) are advanced bioengineering tools designed to replicate human organ functions, boosting drug discovery and providing insights into disease.
  • These systems create 3D environments that can mimic specific human tissues and disease states, allowing researchers to study drug responses, safety, and disease progression more effectively.
  • They also hold future potential for personalized medicine by simulating the unique physiological responses of individual patients, guiding treatment strategies for better health outcomes.
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