Publications by authors named "M Sarfaty"
Prostate cancer (PCa) is the second most diagnosed cancer in men. In recent years, nuclear medicine has played an expanding role in diagnosing, staging, monitoring, and treating PCa. Specifically, the introduction of prostate-specific membrane antigen PET/computed tomography has significantly contributed to detecting locoregional and distant disease.
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- * Researchers analyzed tumor samples from 179 patients and found 23% had harmful DDR gene alterations, which were linked to better pathologic responses after treatment.
- * The findings suggest that these DDR alterations could serve as potential biomarkers for predicting treatment response in bladder cancer patients receiving neoadjuvant chemotherapy.
Sarcopenia is characterized by a loss of muscle mass and function and is often associated with frailty, a syndrome linked to physical disability and shortened survival in various patient populations, including cancer patients. Low serum alanine aminotransferase (ALT) values, serving as a biomarker for sarcopenia, were previously associated with frailty and shortened survival in several cancers. In the current study, we aimed to test the association between low ALT and shorter survival in renal cell carcinoma (RCC) patients and survivors.
View Article and Find Full Text PDFUrgent warnings about the existential threat of climate change are coming from leaders in nearly every sector of society, including virtually all climate scientists, notable heads of civil governments around the globe, the world's top religious leaders, prestigious medical journals, as well as principals of the largest financial firms. Surveys show that the majority of U.S.
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- Sarcopenia, marked by loss of muscle mass and function, is linked to frailty and increased risks of falls, fractures, and physical disability, especially in cancer patients.
- A study analyzed 3,075 bladder cancer patients and found that those with low alanine aminotransferase (ALT) levels, indicating sarcopenia, had significantly lower muscle mass and were older with poorer health metrics.
- The results suggest that low ALT values are associated with a 22% increased mortality risk in bladder cancer patients, highlighting the importance of monitoring muscle health in cancer care.