-heterocyclic scaffolds represent a privileged architecture in the process of drug design and development. It has widespread occurrence in synthetic and natural products, either those that are established or progressing as potent drug candidates. Additionally, numerous novel -heterocyclic analogues with remarkable physiological significance and extended pharmaceutical applications are escalating progressively.
View Article and Find Full Text PDFJ Investig Med High Impact Case Rep
January 2023
We demonstrate the first reported case of peritoneal dialysis (PD)-related peritonitis with . Although previous reports have reported the uncommon similar infection in the larger - complex group of organisms, none have particularly focused on . Furthermore, we present a case of a young man with end-stage renal disease on PD who had a severe infection with .
View Article and Find Full Text PDFHospitalized adult patients suffer from high rates of acute kidney injury (AKI), which puts them at risk for multiple nutrition problems. The etiology and management strategy of AKI has major implications for the management of the hospitalized patient. The purpose of this review is to understand the incidence and management of AKI in hospitalized adult patients and review the challenges to providing adequate nutrition support.
View Article and Find Full Text PDFCurr Gastroenterol Rep
November 2019
Purpose Of Review: To provide an overview of current methods of diagnosis and management of refeeding syndrome in the critically ill patient population.
Recent Findings: Despite recent publications indicating refeeding syndrome (RFS) is an ongoing problem in critically ill patients, there is no standard for the diagnosis and management of this life-threatening condition. There is not a "gold standard" nutrition assessment tool for the critically ill.