Publications by authors named "M Santacatterina"
Article Synopsis
- The THRIVE study aims to adapt a proven PTSD treatment for people using multiple substances while they receive methadone maintenance treatment (MMT), targeting those with a history of trauma and severe PTSD symptoms.
- The adapted treatment includes a condensed schedule of skill-building and narrative therapy sessions designed to help participants manage their PTSD and substance use more effectively.
- The study will involve a preliminary trial with 80 participants to evaluate the intervention's effectiveness and gather insights for future larger trials focused on improving outcomes for this vulnerable population.
Article Synopsis
- Glucocorticoids (GCs) are widely used for treating laryngeal conditions due to their strong anti-inflammatory effects, yet their impact on vocal fold (VF) tissue recovery after injury is not well understood.
- A study induced microflap injuries in rabbits and later administered GCs (dexamethasone, methylprednisolone, and triamcinolone) to assess changes in epithelial structure and barrier function.
- Results showed that GCs helped maintain barrier function and increased epithelial depth over time, but effects varied between the different types of GCs used, indicating possible differences in their therapeutic effectiveness.
Article Synopsis
- Lung cancer remains the leading cause of cancer mortality, but advancements in treating non-small cell lung cancer (NSCLC) have improved patient outcomes through tailored approaches using immune checkpoint inhibitors and genetic testing.
- A study was conducted across multiple pulmonary pathology units in Northern Italy, analyzing biomarker testing data for 1,817 NSCLC patients over 24 months, finding that while most had at least one test, only 36% of advanced cases underwent all five recommended tests.
- The results emphasize the need for comprehensive biomarker testing, as many early-stage patients also exhibited relevant genomic alterations, which is important for future targeted therapies.
Objective: To investigate whether a new preoperative education and discharge planning protocol reduced unexpected discharge delays for patients undergoing reconstructive surgery for head and neck cancer.
Methods: A quality improvement (QI) intervention was implemented in January 2021 with several components to address historically prolonged observed lengths of stay (LOS) with head and neck cancer patients. The intervention added a preoperative educational visit with a head and neck cancer advanced practice provider, a standardized preoperative speech and swallow assessment, a personalized patient care plan document, discussion of inpatient hospital stay expectations, and early discharge planning.
Comparison of four ventilation tubes commonly used in the pediatric population: A retrospective cohort study.
Laryngoscope Investig Otolaryngol
August 2024
Article Synopsis
- The study aimed to compare outcomes related to otorrhea, tympanic membrane perforation, and time to extrusion among four types of ventilation tubes used in children.
- A retrospective review of 387 patients showed that Armstrong beveled tubes resulted in the highest rates of otorrhea, while the Paparella type-I tube had the shortest extrusion time.
- Overall, the study concluded that no single tube type was superior across all complications, suggesting that the choice of ventilation tube should be tailored to individual patient needs.