Publications by authors named "M Santa"
Article Synopsis
- Jejunal diverticulosis is a rare and often asymptomatic condition that can lead to severe issues like intestinal perforation and hemorrhage.
- A 78-year-old patient with multiple health issues presented with acute abdominal pain, and imaging revealed serious intestinal complications, leading to exploratory surgery.
- The case highlights that diagnosing complicated jejunal diverticulosis can be challenging, and surgical intervention is important to prevent serious complications.
Article Synopsis
- Acquired haemophilia (AH) is a rare bleeding disorder caused by the immune system producing autoantibodies that attack clotting factor VIII, even in patients with no previous history of clotting issues.
- A study compared small RNAs collected from patients with AH, classical haemophilia, and healthy donors using advanced sequencing technology, leading to the identification of significant transcript changes.
- The research highlighted that the hemoglobin subunit alpha 1 was the only significantly upregulated transcript in AH patients, but larger studies are needed to confirm these findings and explore the role of non-coding RNAs in the disease's development.
(), the causative agent of human alveolar echinococcosis (AE), is present in the Holarctic region, and several genetic variants deem to have differential infectivity and pathogenicity. An unprecedented outbreak of human AE cases in Western Canada infected with a European-like strain circulating in wild hosts warranted assessment of whether this strain was derived from a recent invasion or was endemic but undetected. Using nuclear and mitochondrial markers, we investigated the genetic diversity of in wild coyotes and red foxes from Western Canada, compared the genetic variants identified to global isolates and assessed their spatial distribution to infer possible invasion dynamics.
View Article and Find Full Text PDFIn a fast-changing and globalized world, parasites are moved across continents at an increasing pace. Co-invasion of parasites and their hosts is leading to the emergence of infectious diseases at a global scale, underlining the need for integration of biological invasions and disease ecology research. In this review, the ecological and evolutionary factors influencing the invasion process of parasites with complex life cycles were analysed, using the invasion of the European strain of Echinococcus multilocularis in North America as a model.
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