Publications by authors named "M Sant'Angelo"
Cancers (Basel)
January 2024
Article Synopsis
- * Researchers conducted a comprehensive literature search and analyzed 39 articles, totaling 68 reported cases, emphasizing the importance of early diagnosis and effective surgical treatment to prevent local recurrence.
- * Despite its generally good prognosis, the review stresses that appropriate care and a multidisciplinary approach can enhance patient outcomes and minimize recurrence, ultimately improving quality of life.
Front Immunol
November 2023
Article Synopsis
- Immunotherapy shows limited benefits for patients with epithelial ovarian cancer (EOC), highlighting the need to better understand local immune dynamics and pathways that suppress T-cell activity against tumors.
- The study analyzed tumor samples from 48 EOC patients to investigate the immune cell composition, focusing on tumor-infiltrating lymphocytes (TILs) using various research methods.
- Findings revealed a unique population of activated T cells in EOC tumors and identified the role of macrophages in both stimulating and inhibiting immune responses, suggesting potential targets for improving immunotherapy efficacy.
Article Synopsis
- The study aims to see how well a special imaging method called 18F-FDG PET/MRI can help figure out how bad endometrial cancer (EC) is before surgery, focusing on deep tissue invasion and lymph node involvement.
- Researchers looked at 35 patients with confirmed EC and compared the imaging results to actual tissue samples to see how accurate the imaging was.
- The results showed that 18F-FDG PET/MRI was very good at detecting lymph node issues and deep tissue invasion in most patients, making it a helpful tool for doctors in staging endometrial cancer.
