Publications by authors named "M Sanchez Pena"
Tracheal tumors in pediatric patients are rare, accounting for 2% of all airway abnormalities and 0.2% of all pediatric tumors. Diagnosis is often delayed due to the heterogeneity of presenting symptoms, such as stridor and wheezing, which are frequently misattributed to other conditions.
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- The Cucurbitaceae family, known for its bioactive compounds, is being studied for its potential in preventing and treating colorectal cancer (CRC).
- Four different extracts from cucurbit leaves and seeds were tested on various CRC cell lines to evaluate their effects on tumor growth and cell health.
- Cold ethanolic extracts showed significant anti-cancer properties, such as inhibiting cell proliferation and angiogenesis, and were linked to specific cell cycle changes and gene expression modifications, suggesting they could enhance CRC treatment strategies.
Anti-CD19 CAR T-cell therapy for primary and secondary CNS lymphomas.
Bone Marrow Transplant
December 2024
Central nervous system lymphomas (CNSL) are a heterogeneous group of generally aggressive tumors whose prognosis varies significantly, being more favorable in patients with primary disease and poorer in those with secondary lymphoma. Current treatments typically involve intensive chemotherapy followed by consolidation with autologous stem cell transplantation or whole-brain radiotherapy. However, if the disease relapses, there is no established standard of care.
View Article and Find Full Text PDFAims/hypothesis: Our aim was to assess sex differences in the efficacy of angiotensin receptor blockers (i.e. losartan and irbesartan) on kidney and cardiovascular outcomes in individuals with type 2 diabetes and diabetic kidney disease.
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- * This systematic review analyzed 276 articles, ultimately focusing on 38 that studied the effects of cannabidiol (CBD) on both somatic stem cells (SSCs) and CSCs.
- * CBD was found to have protective and differentiating effects on SSCs, and an antiproliferative effect on some CSCs, though most studies were conducted in the lab, indicating a need for further research in living organisms.