Publications by authors named "M Sakuyama"
Sous vide, a cooking method that involves vacuum-sealed fish at low temperatures, yields a uniquely tender, easily flaked texture. Previous research on sous-vide tenderization has focused on thermal protein denaturation. On the other hand, the contribution of proteases, activated at low temperatures in fish meat, has been suggested.
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- Betacoronaviruses, including SARS-CoV and MERS-CoV, have caused significant human outbreaks, with SARS-CoV-2 leading to the COVID-19 pandemic.
- The study identified new bat merbecoviruses in two bat species in Japan that are closely related to those found in China.
- These Japanese merbecoviruses lack key mutations needed to infect humans, highlighting the importance of ongoing research on bat coronaviruses for understanding potential risks to human health.
Disease outbreaks and pathogen introductions can have significant effects on host populations, and the ability of pathogens to persist in the environment can exacerbate disease impacts by fueling sustained transmission, seasonal epidemics, and repeated spillover events. While theory suggests that the presence of an environmental reservoir increases the risk of host declines and threat of extinction, the influence of reservoir dynamics on transmission and population impacts remains poorly described. Here we show that the extent of the environmental reservoir explains broad patterns of host infection and the severity of disease impacts of a virulent pathogen.
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- An 84-year-old woman was discovered to have an asymmetric density in her breast through mammography, which led to the identification of a small cyst that later increased in size and developed solid components.
- A core needle biopsy confirmed the presence of intracystic papillary carcinoma, prompting the patient to undergo a partial mastectomy and sentinel lymph node biopsy.
- The histopathological analysis showed the cancerous growth was encapsulated and classified as a non-invasive carcinoma, indicating a positive prognosis for the patient.
Several recent studies have reported that various bat species harbor bat hepatitis E viruses (BatHEV) belonging to the family Hepeviridae, which also contains human hepatitis E virus (HEV). The distribution and ecology of BatHEV are not well known. Here, we collected and screened 81 bat fecal samples from nine bat species in Japan to detect BatHEV RNA by RT-PCR using HEV-specific primers, and detected three positive samples.
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