Publications by authors named "M Saki"

The use of plant extract to synthesize nanoparticles has transformed the area of nanotechnology. Silver nanoparticles (AgNPs) were generated in this work using the leaves of as a reducing and stabilizing agent. The extract of was analyzed using a gas chromatography-mass spectrometer.

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Background: The treatment of multidrug-resistant (MDR-) and extensively drug-resistant tuberculosis (XDR-TB) is a formidable challenge. Treatment of MDR- and XDR-TB using bedaquiline (BDQ) and delamanid (DLM), two newly introduced medications, is steadily increasing. This narrative review aimed to present a concise overview of the existing information regarding BDQ and DLM, and elucidate their antimicrobial characteristics, resistance mechanisms, synergism with other drugs, and side effects.

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Background: This study aims to investigate the frequency of cas1 and cas3 and CRISPR1,2,3 genes in Klebsiella pneumoniae isolates, as well as their connection with antibiotic resistance.

Materials And Methods: 106 K. pneumoniae isolates were identified by biochemical assays and PCR.

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Ethnomedicinal plants are thought to have better prospects of harboring endophytes that produce natural products with pharmacological activities. This study aimed to investigate the antiplasmodial and anticancer properties of secondary metabolites of endophytic fungi from three medicinal plants. The endophytic fungi included Lasiodiplodia theobromae isolated from Cola acuminata, Curvularia lunata Bv4 isolated from Bambusa vulgaris, and Curvularia lunata Eg7 isolated from Elaeis guineensis.

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Article Synopsis
  • The study aimed to investigate plasmid-mediated quinolone resistance (PMQR) genes and biofilm formation in Shigella isolates that are resistant to quinolones, using clinical samples from children under 10 years old.
  • Researchers collected stool samples from 150 patients, identifying 95 Shigella isolates primarily as S. sonnei and S. flexneri, with a notable percentage showing multidrug resistance.
  • The presence of PMQR genes was significant, especially qnrS and qnrA, and biofilm formation was also assessed, indicating a complex challenge for treatment options in these resistant strains.
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