Publications by authors named "M Saeki"

Introduction: In general, platelet counts fluctuate in cancer patients receiving anticancer therapy. It may include thrombocytopenia caused by bone marrow suppression due to cytotoxic anticancer agents and thrombocytosis due to rebound during recovery. This should not be the case in the case of administration of immune checkpoint inhibitors, given their mechanism of action.

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Introduction: Zirconia (ZrO) is highly regarded in dental restoration due to its aesthetic compatibility and mechanical properties that align with biological tissues. This study explores the effects of stabilized ZrO2 on endothelial cell function and extracellular matrix (ECM) remodeling, processes critical to successful osseointegration in dental implants.

Methodology: Human Umbilical Vein Endothelial Cells (HUVECs) were cultured in ZrO -enriched medium under both static and shear stress conditions.

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Article Synopsis
  • Malunion of thumb and finger fractures leads to issues with hand appearance and function, often resulting in rotational deformities in multiple planes.
  • Corrective osteotomy is necessary for addressing these deformities, but accurately measuring the extent of the malunion, especially in the transverse plane, is challenging.
  • A new technique called linkage simulation has been developed to quantify rotational deformities, allowing for better surgical planning and enabling simulations of finger movements and potential outcomes post-surgery.
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Background: As the incidence of obesity increases worldwide, laparoscopic gastrectomy (LG) in obese patients with gastric cancer is more common. It is unclear how visceral fat obesity (obesity disease [OD]) may influence short- and long-term outcomes after LG.

Methods: This study included 170 gastric cancer patients who underwent curative LG at Minoh City Hospital from 2008 to 2020.

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The lack of a widely accessible method for expressing genes of interest in wild-type embryos is a fundamental obstacle to understanding genetic regulation during embryonic development. In particular, only a few methods are available for introducing gene expression vectors into cells prior to neural tube closure, which is a period of drastic development for many tissues. In this study, we present a simple technique for injecting vectors into the amniotic cavity and allowing them to reach the ectodermal cells and the epithelia of endodermal organs of mouse embryos at E8.

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