Publications by authors named "M Sachajko"

Article Synopsis
  • Dietary lipids are crucial for energy, cell structure, and various physiological processes, with PUFAs being examined in diets for pigs in this study.
  • The research focused on two pig breeds, Polish Landrace and PLxDuroc, comparing a normal diet to a PUFAs-enriched one while analyzing liver miRNA profiles for their impact on important agricultural traits.
  • Findings highlighted significant gene interactions related to traits like meat color and fat thickness, revealing specific miRNA clusters linked to muscle development and other essential biological functions.
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The molecular mechanism underlying embryonic implantation is vital to understand the correct communications between endometrium and developing conceptus during early stages of pregnancy. This study's objective was to determine molecular changes in the uterine endometrial proteome during the preimplantation and peri-implantation between 9 days (9D), 12 days (12D), and 16 days (16D) of pregnant Polish Large White (PLW) gilts. 2DE-MALDI-TOF/TOF and ClueGO approaches were employed to analyse the biological networks and molecular changes in porcine endometrial proteome during maternal recognition of pregnancy.

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During the early stages of pregnancy, the uterine endometrium undergoes dramatic morphologic and functional changes accompanied with dynamic variation in gene expression. Pregnancy-stage specific differentially expressed gene (DEG)-transcript-probes were investigated and identified by comparing endometrium transcriptome at 9th day (9D), 12th day (12D) and 16th day (16D) of early pregnancy in Polish large-white (PLW) gilts. Endometrium comparisons between 9D-vs-12D, 9D-vs-16D and 12D-vs-16D of early pregnancy identified 6049, 374 and 6034 highly significant DEG-transcript-probes ( < 0.

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Global gene expression in liver transcriptome varies among cattle breeds. The present investigation was aimed to identify the differentially expressed genes (DEGs), metabolic gene networks and metabolic pathways in bovine liver transcriptome of young bulls. In this study, we comparatively analyzed the bovine liver transcriptome of dairy (Polish Holstein Friesian (HF); = 6), beef (Hereford; = 6), and dual purpose (Polish-Red; = 6) cattle breeds.

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