Sorafenib as Adjuvant Therapy Post-Liver Transplant: A Single-center Experience.

Background: Hepatocellular carcinoma (HCC) has a rising incidence and mortality in North America. Liver transplantation (LT) with adjunctive therapies offers excellent outcomes. However, HCC recurrences are associated with high mortality.

Detection of porcine reproductive and respiratory syndrome virus type 2 in air emissions from grow-finish barns.

Background: Diagnosis of porcine reproductive and respiratory syndrome virus (PRRSV) infections can be accomplished using various sample types and testing methods.  The objective of this study was to evaluate the feasibility of using air emission samples to detect the onset of PRRSV type 2 infections in growing pigs.

Methods: Air emissions and oral fluid samples were collected from three grow-finish barns, stocked with PRRSV-negative pigs every 2 weeks for 14-20 weeks.

PRRSV-2 variant classification: a dynamic nomenclature for enhanced monitoring and surveillance.

Existing genetic classification systems for porcine reproductive and respiratory syndrome virus type 2 (PRRSV-2), such as restriction fragment length polymorphisms and sub-lineages, are unreliable indicators of close genetic relatedness or lack sufficient resolution for epidemiological monitoring routinely conducted by veterinarians. Here, we outline a fine-scale classification system for PRRSV-2 genetic variants in the United States. Based on >25,000 U.

Stress Management Program for Scanxiety in People With Advanced Lung Cancer: Intervention Adaptation and Stakeholder Feedback.

Background: Although scanxiety is common and impactful for people with advanced lung cancer, few interventions address this psychosocial concern.

Aims: To create a stress management program for scanxiety.

Methods: We conducted a structured intervention adaptation process guided by the ADAPT-ITT framework.