Re-Irradiation for the Progressive Pediatric Diffuse Intrinsic Pontine Glioma: A Report on 109 Children From a Single Center.

Background: Diffuse intrinsic pontine glioma (DIPG) is a challenging pediatric tumor that frequently progresses within the first year following local radiotherapy. However, several small studies have suggested that re-irradiation may improve quality of life and extend overall survival.

Patients And Methods: This retrospective study included 109 children who experienced disease progression ≥3 months after their initial radiotherapy, and subsequently received re-irradiation at a single institution.

Clinical and radiographic evaluation of silver diamine fluoride versus mineral trioxide aggregate as indirect pulp capping agents in deeply carious first permanent molars a randomized clinical trial.

Aim: Clinical and radiographic evaluation of SDF versus MTA as indirect pulp capping agents in deeply carious first permanent molars.

Methodology: This study was conducted on (30) first permanent molars indicated for indirect pulp capping (IPC) randomly allocated to either SDF or MTA groups (n = 15). The molars were finally restored with glass hybrid glass ionomer restoration.

Floral diversity and conservation status of vascular plants in arid mountainous areas.

Background: The destructive human activities, encroachment of natural habitats, and hyperarid climate threaten the wild flora of the unprotected mountainous areas facing the Gulf of Suez, Egypt. So, this study aims to revise and give an updated systematic status of the flowering plants growing there to conserve and utilize valuable biodiversity.

Results: This study showed the presence of 136 species, including 7 sub-species of vascular plants, 12 species of monocots, and 124 species dicots belonged to 98 genera and 37 families.

Targeting angiogenic and proliferative mediators by montelukast & trimetazidine Ameliorates thioacetamide-induced liver fibrosis in rats.

Liver fibrosis is a significant health complication with the potential to result in serious mortality and morbidity. However, there is no standard treatment due to its complex pathogenesis. The drug montelukast reversibly and selectively antagonizes the cysteinyl-leukotrienes-1 receptor and reduces inflammation; thus, it is used in the treatment of asthma.

Protective effects of (geranium) oil against cefotaxime-induced hepato-renal toxicity in rats.

Cefotaxime is a broad-spectrum antibiotic targeting Gram-negative bacteria used for diverse infections, but it can be toxic to the stomach, liver, and kidneys. This study explored the protective effects of geranium oil against cefotaxime-induced hepatotoxicity and nephrotoxicity in rats, employing biochemical, histopathological, and immunohistochemical evaluations. Thirty rats were divided into five groups of six animals each one.