Anthropogenic noise pollution has been accelerating at an alarming rate, greatly altering aquatic soundscapes. Animals use various mechanisms to avoid acoustic masking in noisy environments, including altering calling rates or the frequency (pitch) of their vocalizations or increasing the amplitude (loudness) of their vocalizations (i.e.
View Article and Find Full Text PDFImportance: Heterogeneity in development of estrogen receptor (ER)-specific first primary breast cancer exists due to deleterious germline variants in moderate- to high-penetrance breast cancer susceptibility genes, but it is unknown if these associations occur in ER-specific CBC.
Objective: To determine the association of deleterious germline variants in breast cancer susceptibility genes with ER-specific CBC development and whether ER status of the first primary breast cancer modifies these associations.
Design, Setting, And Participants: This case-control study included CBC cases and matched unilateral breast cancer controls from The Women's Environment, Cancer, and Radiation Epidemiology (WECARE) Study, a population-based case-control study.
Background And Objectives: Familial hypercholesterolaemia (FH) is a genetic condition contributing to premature cardiovascular disease. Currently, general practitioners (GPs) do not proactively screen for the condition. This study implemented and evaluated a digital FH self-screening questionnaire administered in general practice.
View Article and Find Full Text PDFTo produce samples for both material testing and molded sheets/parts, this article details an open-source scientific cold and hot press design. It consists of two independent and modular upper and lower plate (929 cm) assemblies each containing four 125 W insulated steel strip heaters. The steel housing for these heaters is entirely modular and designed for ease of manufacture, assembly, and customization.
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