Third-grade school performance in children with special healthcare needs: a prospective cohort study.

Objective: Children with special healthcare needs (SHCN) due to a chronic health condition perform more poorly at school compared with their classmates. We aimed to estimate the effects of past, current, transient, emerging and persistent SHCN on school performance in primary school children.

Methods: Data from the German population-based prospective cohort study ikidS were used.

School well-being in primary school children with chronic illness. A prospective cohort study.

Background: Children with chronic illness perform poorer at school, and school well-being (SWB) may mediate this association. We investigated the association between chronic illness and three domains of SWB in children in first grade.

Methods: Data from a German population-based prospective cohort study were used.

Statistical analysis plan for the FiO-C trial: effects of closed-loop automatic control of the inspiratory fraction of oxygen (FiO-C) on outcomes of extremely preterm infants-a randomized-controlled parallel group multicentre trial for safety and efficacy.

Background: Extremely low gestational age neonates (ELGANs, i.e. those born before 28 weeks postmenstrual age (PMA)) often require supplemental oxygen and frequently experience intermittent hypo- and hyperoxemic episodes.

Associations of preterm birth and neonatal stress exposure with chronic pain in adulthood - Results from the Gutenberg prematurity study.

Although the effect of early childhood stress on central nervous pain processing is well known, studies on the association of prematurity and chronic pain are scarce. This study used data from a single-centre retrospective cohort study followed by a prospective clinical examination and pain assessment. The study was based on data from the local birth registry.