Evaluation of the Accuracy of Standardized Uptake Values of F-fluorodeoxyglucose in Lung Lesions Based on Phantom Studies.

Unlabelled: was to estimate the accuracy of standardized uptake values of F-fluorodeoxyglucose (F-FDG) in lung lesions during positron emission tomography combined with computed tomography (PET/CT) imaging, based on phantom studies performed for different PET/CT scanners.

Materials And Methods: The analysis of the PET/CT with F-FDG data was performed for 86 patients newly diagnosed with the lung lesions: malignant tumors (n=37), benign tumors and inflammatory diseases (n=49). The criteria for inclusion in the study were developed considering the recommendations of the Fleischner Society (2017).

[Comparative analysis of the informative value of 18F-fluorodeoxyglucose and 11C-methionine positron emission tomography in the differential diagnosis of solitary lung masses].

Objective: To study the possibilities of enhancing the efficiency of differential diagnosis of solitary lung masses by optimizing the quantitative analysis of positron emission tomography (PET) data when two radiopharmaceuticals (RP) (18F-fluorodeoxyglucose (18F-FDG) and 11C-methionine) are used alone and in combination.

Material And Methods: A comprehensive examination involving 18F-FDG and 11C-methionine PET was made in 116 patients with solitary lung masses of various genesis. A final diagnosis in the examinees was established from the results of postoperative material morphological analysis and/or laboratory tests and those of X-ray follow-up.

[Sensitivity of PET with 18F-fluorodesoxyglucose in the diagnosis of neuroendocrine tumors of the lungs].

PET with 18F-FDG was administered to 46 patients with different morphological types of neuroendocrine tumors. The method appeared to be highly sensitive in the diagnosis of atypical carcinoids as well as neuroendocrine large-cell lung cancer and small-cell lung cancer. At the same time its imaging capabilities in the detection of typical carcinoids were limited.

[First experience of using positron emission tomography with 11C-choline in prostate cancer (PC)].

Introduction into clinical practice of combined positron emission technology and computer tomography (PET/CT) allows in one study to identify structural and functional abnormalities. The study involves 32 patients who underwent PET/CT with "C-choline, including 5 patients with prostate cancer (PC), 3--with chronic prostatitis and 24--with biochemical PC recurrence. PET/CT with 11C-choline has a high diagnostic efficacy in detection of local recurrence and PC metastases in patients with biochemical PC recurrence.