[Silver nanoparticles induce lipid peroxidation and morphological changes in human lymphocytes surface].

To evaluate toxicity of silver nanoparticles synthesized by using the reverse micelle formation method, the effects of nanoparticles on lipid peroxidation and morphological changes of cell membranes in human lymphocytes were studied. It was found that under the influence of nanoparticles a reduction in cell viability and formation of excessive levels of reactive oxygen species were observed. Silver nanoparticles at different concentrations activate the processes of lipid peroxidation and, as a consequence, led to morphological changes in human lymphocytes.

Novel 'Si-C' carbosilane dendrimers as carriers for anti-HIV nucleic acids: studies on complexation and interaction with blood cells.

Treatment of HIV infection by gene therapy is a promising tool for combating AIDS. One of the primary limitations of gene therapy is the effective delivery of nucleic acids to the target cells. Dendrimers are nanoparticles that are increasingly being used as nucleic acid vehicles.