Retrieval of an Aveir Leadless Pacemaker With a Standard Retrieval Catheter by Releasing the Wedged Docking Button Using a Loop Wire Technique.

Introduction: The docking button of the Aveir leadless pacemaker (LP) is occasionally difficult to access due to its inappropriate position in the right ventricle (RV).

Methods And Results: We report a case where the Aveir LP was successfully retrieved by releasing the wedged docking button in the inferior wall of the RV using a loop wire technique.

Conclusion: The loop wire technique may be useful to change the position of the Aveir LP.

Hollow Fiber Microreactor Combined with Digital Twin to Optimize the Antimicrobial Evaluation Process.

In order to reproduce pharmacokinetics (PK) profiles seen in vivo, the Hollow Fiber Infection Model (HFIM) is a useful in vitro module in the evaluation of antimicrobial resistance. In order to reduce the consumption of culture medium and drugs, we developed a hollow fiber microreactor applicable to the HFIM by integrating the HFIM function. Next, we constructed a novel control method by using the "digital twin" of the microreactor to achieve precise concentration control.

Crosstalk between prolactin, insulin-like growth factors, and thyroid hormones in feather growth regulation in neonatal chick wings.

The elongation of primary feathers in neonatal chicks is delayed by the late-feathering K gene located on the Z chromosome. We recently found that the K gene slows feather growth by reducing the number of functional prolactin (PRL) receptor (PRLR) dimers. In this study, we investigated the molecular mechanisms by which PRL promotes feather elongation.