Publications by authors named "M S Segal"
Purpose Of Review: The purpose of this review is to provide an update regarding recent research and recommendations in the care of mild traumatic brain injury (mTBI).
Recent Findings: New diagnostic criteria for mTBI have recently been developed by the American Congress of Rehabilitation Medicine through the Delphi method and this will help to standardize assessment, diagnosis, and treatment. Symptoms of mTBI are diverse and can sometimes become persistent.
Failure to rapidly diagnose tuberculosis disease (TB) and initiate treatment is a driving factor of TB as a leading cause of death in children. Current TB diagnostic assays have poor performance in children, and identifying novel non-sputum-based TB biomarkers to improve pediatric TB diagnosis is a global priority. We sought to develop a plasma biosignature for TB by probing the plasma proteome of 511 children stratified by TB diagnostic classification and HIV status from sites in four low- and middle-income countries, using high-throughput data-independent acquisition mass-spectrometry (DIA-PASEF-MS).
View Article and Find Full Text PDFExtensive research has been focused in the past century on structural, physiological, and molecular attributes of the hippocampus. This interest was created by the unique involvement of the hippocampus in cognitive and affective functions of the brain. Functional analysis revealed that the hippocampus has divergent properties along its axial dimension to the extent that the dorsal sector (dorsal hippocampus, DH) has different connections with the rest of the brain than those of the ventral sector (VH).
View Article and Find Full Text PDFObjective: To understand mortality and secondary outcomes in patients with both end-stage kidney disease (ESKD) and chronic limb-threatening ischemia (CLTI) after no procedural treatment, primary amputation, endovascular treatment, and open surgery.
Summary Background Data: ESKD and CLTI commonly cooccur and limited prior work has demonstrated poor outcomes including one-year survival despite treatment.
Methods: We conducted a retrospective national cohort study of United States Renal Data System data from January 1, 2016 to December 31, 2019 to determine mortality, major postoperative complications, and other outcomes.
Article Synopsis
- Poly(ε-caprolactone) (PCL) is commonly used in the biomedical field, but it has a long degradation time, which limits its applications.
- Researchers developed a semiaromatic polyester-ether (SAEE) PCL copolymer using a salicylic acid monomer that alters PCL's structural properties, resulting in a decrease in melting and crystallization temperatures with increased SAEE content.
- The study found that by adjusting the SAEE percentage, they could significantly enhance the thermal, mechanical, and degradation characteristics of the PCL copolymers, achieving total mass loss in a shorter timeframe while preserving beneficial biological properties.