Publications by authors named "M S Sakashita"
The prognosis of adult T-cell leukemia/lymphoma (ATL) with primary central nervous system (CNS) involvement has been unclear since the advent of new therapies. Recently, we have shown that flow cytometric CD7/CADM1 analysis of CD4 + cells (HAS-Flow) is useful to detect ATL cells that are not morphologically diagnosed as ATL cells. We investigated the role of CNS involvement in ATL using cytology and HAS-Flow by analyzing cerebrospinal fluid (CSF) from 73 aggressive ATL cases.
View Article and Find Full Text PDFBackground: This study examined the relationship between the disciplinary diversity of research teams and research output (RO) in allergy and immunology programs funded by the National Institutes of Health (NIH) in the United States, Medical Research Council (MRC) in the United Kingdom, and Japan Society for the Promotion of Science (JSPS).
Methods: Using a dataset containing 1243, 3645, and 1468 articles funded by the NIH, MRC, and JSPS, respectively, we analyzed the correlation between disciplinary diversity and RO in allergy and immunology programs that received grants from 2017 to 2021. Diversity was measured using All Science Journal Classification codes counts, Shannon-Wiener index, and newly developed Omnidisciplinary index (o-index).
Article Synopsis
- Allergic fungal rhinosinusitis (AFRS) and eosinophilic chronic rhinosinusitis (ECRS) both involve nasal polyps but differ primarily in the presence of fungal infections in AFRS.
- A study analyzed nasal polyps from patients with AFRS, ECRS, and non-ECRS to assess immune cell types, revealing that AFRS had more M2 macrophages compared to ECRS, which is linked to the fungal infection.
- The findings underline the unique immune responses in AFRS versus ECRS, particularly the role of M2 macrophages in AFRS's development.
Background: Hay fever (HF) presents with various symptoms, including allergic conjunctivitis and rhinitis, and requires cross-organ treatment. This study assessed the impact of the coronavirus disease 2019 (COVID-19) pandemic on HF treatment trends.
Methods: This retrospective cohort study utilized data from the JMDC database collected between January 2018 and May 2021.