Publications by authors named "M S Runge"

Harbour seals () are the most common pinniped species in the Wadden Sea of Schleswig-Holstein, Hamburg and Lower Saxony, Germany. Their numbers have recovered after significant depletion due to viral outbreaks and effects of anthropogenic activities like pollution and habitat disturbance. Within the Wadden Sea National Park of Lower Saxony the harbour seal is protected.

View Article and Find Full Text PDF
Article Synopsis
  • One Health is a concept that tries to keep people, animals, plants, and the environment healthy together.
  • The study looked at how SARS-CoV-2, the virus causing COVID-19, spreads between white-tailed deer and could affect humans.
  • They discovered that working together with different groups is better at stopping the virus than if each group acted alone.
View Article and Find Full Text PDF

Vaccine effectiveness (VE) studies provide real-world evidence to monitor vaccine performance and inform policy. The WHO Regional Office for the Eastern Mediterranean supported a regional study to assess the VE of COVID-19 vaccines against different clinical outcomes in four countries between June 2021 and August 2023. Health worker cohort studies were conducted in 2707 health workers in Egypt and Pakistan, of whom 171 experienced symptomatic laboratory-confirmed SARS-CoV-2 infection.

View Article and Find Full Text PDF
Article Synopsis
  • Squamoid eccrine ductal carcinoma is a rare tumor with characteristics that fall between squamous cell carcinoma (SCC) and certain sweat gland carcinomas, leading to debates on its classification.
  • The study examined 15 cases of this carcinoma, revealing that most cases had UV signature mutations and TP53 mutations as the most common genetic alterations.
  • Transcriptome analysis indicated that this carcinoma expresses 364 genes more and 525 genes less compared to SCC and sweat gland tumors, reinforcing the idea that it has an intermediate phenotype between these cancer types.
View Article and Find Full Text PDF
Article Synopsis
  • A Coxiella burnetii vaccination program targeted doelings on a German goat farm to reduce bacterial shedding, beginning with adult vaccinations in 2018 and continuing with two doses for doelings from 2019 to 2021.
  • Monitoring involved vaginal swabs and bulk tank milk samples, revealing some ongoing shedding despite positive trends in antibody levels among vaccinated goats.
  • Results showed that while double vaccination produced lasting antibody responses, it did not completely eliminate C. burnetii shedding, indicating the need for further research on the immune response.
View Article and Find Full Text PDF