Publications by authors named "M S Noah"
Objectives: This study aims to assess the magnitude of opportunistic infection (OI) and to identify factors associated with OIs among people living with HIV (PLHIV) on antiretroviral treatment (ART), attending HIV care and treatment clinics.
Design: A hospital-based cross-sectional study.
Setting: The study was conducted at Muhimbili National Hospital, Mwananyamala and Temeke Regional Referral Hospitals, in Dar es Salaam, Tanzania.
Article Synopsis
- Testosterone plays a significant role in promoting the proliferation, migration, and invasion of glioma cells by upregulating glial cell line-derived neurotrophic factor (GDNF).
- The study found that testosterone triggers inflammation in brain neurons and astrocytes, leading to the recruitment of pro-inflammatory macrophages, which contributes to tumor growth.
- Overall, the research indicates that testosterone influences brain tumor development through its effects on GDNF and the inflammatory response in the surrounding neural microenvironment.
Background: Intestinal schistosomiasis is one of the most common neglected tropical diseases in Tanzania. Despite massive praziquantel administration, data from Northern Tanzania have reported a prevalence of up to 93.2%.
View Article and Find Full Text PDFThe ethyl acetate fraction, the stem bark and the residual methanolic extracts from the leaves of (Sterculiaceae) led to the isolation of two new compounds: Heterophynone () and methyl ester of Colic acid (), along with four known triterpenes: betulinic acid (), oleanolic acid (), ursolic acid () and chletric acid (). Structures of compounds were established by different spectroscopic methods that included 1D and 2D NMR experiment. The antimicrobial activity of isolated compounds was evaluated against two yeasts, NR 29456 and 1415; and five Gram-positive bacterial, , NR 46003, NR46374 and HM 601).
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