Publications by authors named "M S Mendonca"
Article Synopsis
- The study explores how modifying the cyclodextrin (CD) ring structure with hydroxyl groups and functional groups enhances its potential for delivering therapeutic siRNA.
- Multiple cationic amphiphilic CDs were synthesized and evaluated for their ability to encapsulate siRNA and improve gene silencing efficiency in A549-luc cells.
- Key findings revealed that CDs with primary amine modifications at positions C2 and C3 significantly increased gene knockdown levels, achieving up to 80% with specific linker modifications.
Addressing the Persistent Social Challenges of Very Preterm Birth.
Paediatr Perinat Epidemiol
December 2024
Article Synopsis
- The genus Prabhergia, previously only found in Asia, has been documented for the first time in Brazil.
- Its defining features include unique body structures like pseudocelli on tergites and a specific arrangement of sensory organs on the antennae.
- A new species named Prabhergia mana sp. nov. has been identified from specimens located in bee nests within Rio de Janeiro's Botanical Garden.
Background: The Giacomini vein (GV) can transfer reflux from perineal veins, tributary veins, and perforators of the thigh to the small saphenous vein (SSV). Vascular ultrasound with Doppler (VUD) is the preferred method for detecting reflux in specific veins such as the GV.
Objective: To identify GV depth and diameter, reflux in the GV, and presence of reflux in the SSV caused by the GV.