The Role of Palliative Nursing in the Context of Immunotherapies: A Scoping Review of Patient- and Family-Centered Care Considerations.

Immunotherapies are increasingly used to treat advanced cancers and can extend survival in some patients. The potential for longer survival may inflate prognosis expectations among patients and caregivers and delay palliative care. This review sought to identify issues impacting patients and caregivers that influence specialized palliative care use in the context of immunotherapies.

Understanding the role of nutritional status on the outcomes of nonvariceal upper gastrointestinal bleeding: Findings from a retrospective cohort analysis.

Background & Aims: Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common cause of hospitalization worldwide. Malnutrition, on the other hand, varies in prevalence and closely correlates with age and comorbidities. Though malnutrition is linked to poor outcomes generally, its impact on NVUGIB patients remains unexplored.

Prevalence and proposed aetiologies of dystonias or yips in athletes playing overhand sports: a scoping review protocol.

Introduction: Sports-related dystonia, also called the yips, are often seen in athletes in multiple sports. In this condition, an athlete abruptly loses the ability to perform a repetitive motion performed thousands of times. Such occurrences are often assumed to be psychological in nature, and thus evaluation for other causes is often lacking.

Shared Decision-Making Tools Implemented in the Electronic Health Record: Scoping Review.

Background: Patient-centered care promotes the involvement of patients in decision-making related to their health care. The adoption and implementation of shared decision-making (SDM) into routine care are constrained by several obstacles, including technical and time constraints, clinician and patient attitudes and perceptions, and processes that exist outside the standardized clinical workflow.

Objective: We aimed to understand the integration and implementation characteristics of reported SDM interventions integrated into an electronic health record (EHR) system.

Upregulation of Na/H Exchanger in Astrogliosis and Early Alzheimer's Disease Pathogenesis.

Reactive astrogliosis has been indicated as one of the earliest pathological biomarkers in Alzheimer's Disease (AD) pathology. We previously reported that upregulation of the Na/H exchanger isoform 1 (NHE1) protein in reactive astrocytes contributes to neuroinflammation and cognitive function deficits in murine models of ischemic stroke and vascular stenosis. In this study, we utilized AD human post-mortem and APP/PS1dE9 (APP) transgenic mouse brain tissues to determine whether NHE1 upregulation in astrocytes is associated with AD pathogenesis.