Publications by authors named "M S Khurana"

Article Synopsis
  • The study aimed to explore the clinical profile of visual impairment (VI) in patients with primary open-angle glaucoma (POAG) and the effectiveness of low-vision devices (LVD).
  • Researchers analyzed case records from a low-vision care clinic, focusing on visual acuity changes before and after using LVD, and found significant improvements in vision for both distance and near vision.
  • The results indicated that LVD particularly benefited patients with severe visual field loss, enhancing their near vision and increasing the proportion of patients earning income after rehabilitation, highlighting the importance of tailored management for POAG patients with VI.
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Introduction And Clinical Importance: Goldenhar syndrome (GS) manifests as a triad of ocular, auricular, and vertebral anomalies. We present a rare case report presenting with monocular elevation deficiency (MED) in association with GS secondary to radiologically proven vascular insufficiency.

Case Presentation: A 9-year-old male presented with drooping of the upper eyelid in the right eye (OD), absence of right ear, and swelling near the ear remanent.

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Article Synopsis
  • The study investigates the factors that prevent parents from seeking early intervention for strabismus in their children, aiming to find ways to improve access to care.
  • Researchers surveyed 110 parents of children with strabismus at a health clinic in India, examining their knowledge about the condition and reasons for not pursuing treatment.
  • Results showed that many parents are worried about surgical outcomes and costs, and educational efforts are needed to change perceptions about the importance and nature of strabismus treatment.
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Vast amounts of pathogen genomic, demographic and spatial data are transforming our understanding of SARS-CoV-2 emergence and spread. We examined the drivers of molecular evolution and spread of 291,791 SARS-CoV-2 genomes from Denmark in 2021. With a sequencing rate consistently exceeding 60%, and up to 80% of PCR-positive samples between March and November, the viral genome set is broadly whole-epidemic representative.

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Article Synopsis
  • The study investigates the impact of switching to narrow-spectrum antibiotics for treating E. coli bacteraemia, evaluating changes in resistance rates, antibiotic usage, and mortality.
  • The research employs a deterministic state-transition model with three scenarios to analyze outcomes over five years, highlighting trade-offs between resistance and survival rates.
  • Findings suggest that while using the narrowest spectrum antibiotics can reduce resistance to second and third-line options, it may increase first-line resistance and mortality; however, optimizing treatment duration and reducing mortality rates are key to making this switch feasible.
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