Publications by authors named "M S J Pais"

AI, especially ChatGPT, is impacting healthcare through applications in research, patient communication, and training. To our knowledge, this is the first study to examine ChatGPT-4's ability to analyze images of lower leg defects and assesses its understanding of complex case reports in comparison to the performance of board-certified surgeons and residents. We conducted a cross-sectional survey in Switzerland, Germany, and Austria, where 52 participants reviewed images depicting lower leg defects within fictitious patient profiles and selected the optimal reconstruction techniques.

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Biological sex strongly impacts tuberous sclerosis complex (TSC) symptoms like epilepsy and autism. However, the mechanisms driving this influence remain largely unknown. Here, we discuss how sex-specific changes in brain synapses and neural networks may drive these differences, offering insights that could be crucial for developing targeted therapies for TSC.

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The distance between the mid-clavicle and nipple (MCN) is crucial in planning reduction mammoplasties. MCN has been shown to be superior in achieving nipple-areola complex symmetry. However, there is great variability in clavicle anatomy.

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Brain dopamine type 2 and 3 receptors (D2/3R) have been postulated to play a role in obesity. However, results from molecular neuroimaging studies exploring these receptors in obesity are not consensual. These inconsistencies may be due to the distinct characteristics of radiotracers that confound the interpretation of D2/3R assessment.

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Article Synopsis
  • - The study explores how psychedelics, specifically DMT, may enhance social cognition and help in treating disorders related to emotional and reward processing issues through changes in brain connectivity.
  • - Using resting-state fMRI, researchers looked at the effects of DMT on brain areas important for understanding emotions and social interactions in eleven experienced users, comparing results between DMT inhalation and a control condition.
  • - Findings showed that DMT increased connectivity in regions linked to social cognition, including the supramarginal gyrus and amygdala, suggesting it may improve emotional and social processing, which could have therapeutic implications.
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