Publications by authors named "M S Iyisoy"

Depression is responsible for neuropathies such as decreased neurogenesis and increased dendritic atrophy. There is information that antidepressant treatments have an effect by increasing hippocampal neurogenesis and neurotrophic factor expression. The neuropeptide Y1 (NPY1R) receptor agonist has been suggested to have anxiolytic effects.

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Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease with varied clinical manifestations affecting multiple organ systems. This study aimed to investigate the association between the systemic immune-inflammation index (SII) and disease activity, as well as proteinuria levels in patients with SLE. Methodology A total of 141 patients diagnosed with SLE and 99 control subjects were included in this retrospective study.

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Introduction: The distinction between benign and borderline epithelial ovarian tumors is important because treatment and follow-up strategies differ

Objective: We aimed to evaluate benign, borderline, and malignant epithelial ovarian tumors using MRI features and contributed to the preoperative evaluation.

Methods: MRIs of 81 patients (20 bilateral), including 31 benign, 27 borderline, and 23 malignant, who had pelvic imaging between 2013-2020, were evaluated retrospectively. The evaluation was made blindly to the pathology result by two radiologists with MRI scoring and features that we determined.

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Article Synopsis
  • Alzheimer's disease (AD) is characterized by progressive dementia and affects cholinergic systems, with neurokinin 3 receptor (NK3R) playing a role in memory and learning.
  • A study was conducted using 50 male Wistar albino rats that were divided into various groups, including AD and NK3R agonist-treated groups, to assess the behavioral and neurotransmitter changes after administering the NK3R agonist senktide.
  • Results showed that while the AD group struggled with learning in the Morris water maze (MWM) test, the NK3R agonist improved cognitive functions and learning potential in the AD model, likely through cholinergic mechanisms.
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