The measurement of microplastics in surface water and their impact on histopathological structures in wading birds of district Lahore.

Plastics are globally considered a significant threat, particularly to metropolitan areas, due to the extensive use of plastic products. This research is the first of its kind to document microplastics contamination and its effects on Red wettled lapwing (Vanellus indicus). The concentration of microplastics (MPs) was measured from surface water at different locations including canals and drains, which are the primary sources of MPs pollution in the metropolitan city Lahore, Pakistan.

Nanotechnology in Parkinson's Disease: overcoming drug delivery challenges and enhancing therapeutic outcomes.

The global prevalence of Parkinson's Disease (PD) is on the rise, driven by an ageing population and ongoing environmental conditions. To gain a better understanding of PD pathogenesis, it is essential to consider its relationship with the ageing process, as ageing stands out as the most significant risk factor for this neurodegenerative condition. PD risk factors encompass genetic predisposition, exposure to environmental toxins, and lifestyle influences, collectively increasing the chance of PD development.

Optimization & enhancement of KGeCl-based perovskite solar cells through charge transport layer engineering.

The growing demand for efficient, stable, and environmentally friendly photovoltaic technologies has motivated the exploration of nontoxic perovskite materials such as KGeCl. However, the performance of KGeCl-based perovskite solar cells (PSCs) depends heavily on the compatibility of charge transport layers (CTLs) and optimization of device parameters. In this study, six PSC configurations were simulated using SCAPS-1D software, incorporating CTLs such as Alq, CSTO, VO, PB, and SbS.

Success Rates of Dental Implants in Patients With Diabetes: A Systematic Review.

This systematic review evaluates the success rates of dental implants in patients with type 2 diabetes mellitus, focusing on outcomes such as implant survival, marginal bone loss, and peri-implant biomarkers. A comprehensive literature search was conducted across multiple databases, including PubMed, Cochrane, Embase, Scopus, and Web of Science, to identify relevant systematic reviews and meta-analyses. Four studies were included, encompassing diverse populations and interventions.

Heterogeneity of the Treatment Effect with PARP Inhibitors in Metastatic Castration-resistant Prostate Cancer: A Living Interactive Systematic Review and Meta-analysis.

Background And Objective: Selection of patients harboring mutations in homologous recombination repair (HRR) genes for treatment with a PARP inhibitor (PARPi) is challenging in metastatic castration-resistant prostate cancer (mCRPC). To gain further insight, we quantitatively assessed the differential efficacy of PARPi therapy among patients with mCRPC and different HRR gene mutations.

Methods: This living meta-analysis (LMA) was conducted using the Living Interactive Evidence synthesis framework.