Quantifying joystick interactions and movement patterns of toddlers with disabilities using powered mobility with an instrumented Explorer Mini.

Powered mobility technology can be a powerful tool to facilitate self-initiated exploration and play for toddlers with motor disabilities. The joystick-controlled Permobil Explorer Mini is currently the only commercially available powered mobility device for children ages 1-3 years in the United States. However, many open questions persist regarding how joystick-based mobility technologies should be designed to optimally suit the developmental needs of toddlers.

Recombinant factor VIIa: new insights into the mechanism of action through product innovation.

Management of bleeding in persons with hemophilia and inhibitors involves treatment with bypassing agents, including recombinant activated factor VII (rFVIIa). Two rFVIIa products are commercially approved for use in the United States and the European Union. Eptacog alfa and eptacog beta share the same amino acid sequence but differ in posttranslational modifications.

Alcohol drinking is associated with greater calcium activity in mouse central amygdala dynorphin-expressing neurons.

Unlabelled: Alcohol use disorder (AUD) is a chronic disease that poses significant economic burden and health risks. It is pivotal to better understand brain mechanisms engaged by alcohol that promote misuse. The central amygdala (CeA) has emerged as a key mediator of excessive preclinical alcohol consumption.

U.S. Naval Medical Research Unit SOUTH's Contributions to Strengthening Global Health Security in Peru and Across Latin America.

Infectious diseases (IDs) contribute to major causes of mortality and chronic morbidity in Central and South America. Interest in improving general understanding, prevention, and treatment options motivates the U.S.

Assessment of students' ability to represent determinants of health and health systems science content on concept maps in a pre-clerkship curriculum.

Background: Hackensack Meridian School of Medicine (HMSOM) was founded on a vision of addressing the determinants of health (DoH) in the daily practice of medicine. The school has an active learning curriculum partially conducted through a small group modified problem-based-learning entitled Patient Presentation Problem-based-learning Curriculum (PPPC). This course includes a Monday discussion of a patient case and a Friday small group session includes concept mapping of the week's basic, clinical, and health systems science (HSS) content.