Comment on "Perturbation theory of scattering for grazing-incidence fast-atom diffraction", by W. Allison, S. Miret-Artés and E. Pollak, , 2022, , 15851.

In this comment we discuss some aspects of , 2022, , 15851, by Allison , an article intensely motivated by our study of grazing incidence fast atom diffraction (GIFAD) for He-KCl(001) [G. A. Bocan, H.

Diazepam-Induced Down-Regulation of the GABA receptor α1 Subunit, as mediated by the activation of L-Type Voltage-Gated calcium Channel/Ca/Protein kinase a signaling cascade.

Benzodiazepines are among the most prescribed drug class worldwide to treat disorders such as anxiety, insomnia, muscle spasticity, and convulsive disorders, and to induce presurgical sedation. Although benzodiazepines exhibit a high therapeutic index and low toxicity in short-term treatments, prolonged administration induces tolerance to most of their therapeutic actions. The mechanism of this tolerance remains unclear.

Grazing incidence fast atom and molecule diffraction: theoretical challenges.

This perspective article reviews the state-of-the-art of grazing incidence fast atom and molecule diffraction (GIFAD and GIFMD) simulations and addresses the main challenges that theorists, aiming to provide useful inputs in this topic, are facing. We first discuss briefly the methods used to build accurate potential energy surfaces describing the interaction between the projectile and the surface. Subsequently, we focus on the dynamics simulation methods for GIFAD, a phenomenon that has received a lot of experimental attention since 2007, when the first measurements were published.

Regulation of GABA Receptors Induced by the Activation of L-Type Voltage-Gated Calcium Channels.

GABA receptors are pentameric ion channels that mediate most synaptic and tonic extrasynaptic inhibitory transmissions in the central nervous system. There are multiple GABA receptor subtypes constructed from 19 different subunits in mammals that exhibit different regional and subcellular distributions and distinct pharmacological properties. Dysfunctional alterations of GABA receptors are associated with various neuropsychiatric disorders.