A 180-day clinical investigation of the tooth whitening efficacy of a bleaching gel with added amorphous calcium phosphate.

Objective: The purpose of this study was to determine if there are any significant long-term clinical benefits, or side effects, caused by the addition of amorphous calcium phosphate (ACP) to a professional, 16% peroxide bleaching gel.

Methodology: This study examined the effect of bleaching gel with added ACP in a subset of subjects (n=27) from a previously published, short-term (n=50) study, in which two groups were assigned to use either an experimental ACP-containing gel or a similar "control" gel. Both groups used the product for four hours (or overnight) daily for 14 days.

The clinical performance of professionally dispensed bleaching gel with added amorphous calcium phosphate.

Background: The authors undertook a study to measure how the addition of amorphous calcium phosphate (ACP) to a professionally dispensed 16 percent carbamide peroxide equivalent bleaching gel affects tooth color and dentinal hypersensitivity.

Methods: The authors assigned two groups to use either the test gel containing ACP or a control gel. Both groups used their respective products for three hours daily for 14 days.

The effect of a triclosan/copolymer/fluoride liquid dentifrice on interproximal enamel remineralization and fluoride uptake.

Background: The authors measured the enamel remineralization of dental interproximal surfaces by a triclosan/copolymer/fluoride liquid dentifrice to test its performance against that of a standard toothpaste.

Methods: In a randomized, crossover, blinded, in situ protocol, the authors fitted 19 healthy adult subjects with mandibular appliances holding bilateral, interproximal bovine enamel slabs. They measured initial abrasion levels and fluoride content.

Clinical comparison of the stain-removal efficacy of a novel liquid whitening gel containing 18% carbamide peroxide and a commercially available whitening dentifrice.

The objective of this examiner-blind clinical study was to compare the extrinsic tooth-stain removal efficacy of a novel, nontray, "paint-on" liquid whitening gel containing 18% carbamide peroxide (Colgate Simply White Clear Whitening Gel) with a commercially available whitening dentifrice. After a baseline examination for extrinsic tooth stain, qualifying adult men and women from Canada were randomized into two treatment groups balanced for age, gender, and level of extrinsic tooth stain. Subjects were instructed to brush their teeth twice daily (morning and evening) for 1 minute with their assigned dentifrice (Group 1: nonwhitening dentifrice; Group 2: whitening dentifrice).