Publications by authors named "M S Giacomello"
Article Synopsis
- This study presents a novel in vitro muscle-derived cell line from a stranded male Cuvier's Beaked whale, facilitating research on its myogenic cells.
- The characterization involved various assays that assessed growth rate, fusion index, and chromosomal analysis, showing the cells' capability to fuse into multinucleated myotubes over time.
- The findings highlight the potential of this whale cell line for understanding cetacean muscle physiology and assessing the impacts of water pollutants through in vitro models.
Skin cutaneous melanoma (SKCM) is the deadliest form of skin cancer due to its high heterogeneity that drives tumor aggressiveness. Melanoma plasticity consists of two distinct phenotypic states that co-exist in the tumor niche, the proliferative and the invasive, respectively associated with a high and low expression of MITF, the master regulator of melanocyte lineage. However, despite efforts, melanoma research is still far from exhaustively dissecting this phenomenon.
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