Social context modulates active avoidance: Contributions of the anterior cingulate cortex in male and female rats.

Actively avoiding danger is necessary for survival. Most research on active avoidance has focused on the behavioral and neurobiological processes when individuals learn to avoid alone, within a solitary context. Therefore, little is known about how social context affects active avoidance.

Examining the malleability of implicit views of aging in middle-aged and older adults.

Negative views of aging (VoA) present a motivational barrier to healthy aging. Although prior interventions have demonstrated success in making adults' negative VoA more positive, reliance on self-report-based explicit measures is insufficient to examine whether these interventions also affected individuals' implicit VoA. Thus, this study assessed the impact of the AgingPLUS program, a 4-week psychoeducational intervention, on implicit measures of VoA in a randomized controlled trial.

Persistent tailoring of MSC activation through genetic priming.

Mesenchymal stem/stromal cells (MSCs) are an attractive platform for cell therapy due to their safety profile and unique ability to secrete broad arrays of immunomodulatory and regenerative molecules. Yet, MSCs are well known to require preconditioning or priming to boost their therapeutic efficacy. Current priming methods offer limited control over MSC activation, yield transient effects, and often induce the expression of pro-inflammatory effectors that can potentiate immunogenicity.

Walking performance differs between people with multiple sclerosis who perform distinct types of exercise.

To determine whether walking performance differed between people with multiple sclerosis (MS) who performed distinct types, volumes and intensities of exercise. Forty-five people with relapsing-remitting MS performed two trials of the 2-min walk test, one at a preferred speed and another at a fast speed. Gait metrics were measured by wireless inertial sensors.

Psychometric Properties and Measurement Invariance of the Awareness of Age-Related Change Short Form in Older Adult Samples From Taiwan and Germany.

Background And Objectives: This study examined the psychometric properties and measurement invariance of the 10-item Awareness of Age-Related Change Short Form (AARC-SF) questionnaire in a Chinese-speaking sample of older adults in Taiwan.

Research Design And Methods: Data from 292 participants (Mage = 77.64 years) in the Healthy Aging Longitudinal Study in Taiwan cohort were used for Study 1, whereas data from young-old adult samples in Germany were used for Study 2.