Publications by authors named "M S Cha"
Background: In professional basketball, Jones fractures are among the most common cause of lower extremity stress injury. Despite its prevalence, there is a paucity of research on the impact of Jones fractures on athletic performance in the National Basketball Association (NBA).
Purpose: To determine the impact of Jones fractures on return to play and performance among NBA players when compared with preinjury values and healthy matched controls.
Aims & Objectives: This study characterized the independent association between insurance type and healthcare outcomes in patients undergoing total joint arthroplasty (TJA).
Materials &methods: National data identified patients who underwent total hip, knee, shoulder, elbow, ankle or wrist joint arthroplasty surgery from 2012 to 2020 for osteoarthritis. Medicaid, Medicare≥65 years old, Medicare<65 years old, and uninsured patients were matched to privately insured patients based on age, sex, and comorbidities.
Article Synopsis
- This study analyzes the impact of various comorbidities, such as obesity and hypertension, on hospital charges, costs, and length of stay for patients undergoing total knee arthroplasty (TKA).
- A total of over 1 million patients from a national database were examined, revealing significant variation in hospital charges and costs associated with specific comorbidities like weight loss and pulmonary hypertension.
- The findings suggest that addressing certain modifiable and non-modifiable health issues through targeted programs could help reduce overall hospital expenses and length of stay for TKA patients.
Article Synopsis
- Succinic acid is important for food additives, dietary supplements, and biodegradable polymers, and its production has gained interest due to environmental and economic factors.
- The study improved succinic acid production from lignocellulosic biomass by genetically modifying strains to overexpress specific genes, leading to a 1.3-fold increase in production.
- Fed-batch fermentation produced 50 g/l of succinic acid, and batch fermentation from barley straw yielded 22.2 g/l, suggesting that using agricultural waste for succinic acid production could be a sustainable industrial approach.
Sphingolipids are vital membrane components in in mammalian cells, plants, and various microbes. We aimed to explore and exploit the sphingolipid biosynthesis pathways in an oleaginous and dimorphic yeast Yarrowia lipolytica by constructing and characterizing mutant strains with specific gene deletions and integrating exogenous genes to enhance the production of long-chain bases (LCBs) and glucosylceramides (GlcCers). To block the fungal/plant-specific phytosphingosine (PHS) pathway, we deleted the SUR2 gene encoding a sphinganine C4-hydroxylase, resulting in a remarkably elevated secretory production of dihydrosphingosine (DHS) and sphingosine (So) without acetylation.
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