Publications by authors named "M S Avanzi"

Background And Aim Of The Work: A cervical spinal cord injury often affects hand control, causing ineffective grasping and handling functions, with a negative impact on patient's independence and quality of life. Literature recognises scientific evidence only for surgical or instrumental re-education approaches. The purpose of this study is to present the "functional hand" protocol, a physiotherapy tool that, to date, represents a good clinical practice but has no supporting literature.

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Article Synopsis
  • The ZUMA-5 trial evaluated axicabtagene ciloleucel CAR T-cell therapy for patients with relapsed or refractory indolent non-Hodgkin lymphoma, focusing on those who had already undergone multiple treatment lines.
  • This phase 2 study involved patients aged 18 or older across various cancer centers in the US and France, requiring specific eligibility criteria, including certain types of lymphoma and prior therapies.
  • The primary goal was to determine the overall response rate (complete and partial responses) within a specified follow-up period, with the study now closed to new participants.
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The use of immunotherapy in cancer treatment over the past decade has resulted in significant advances and improvements in cancer patients survival with the use of checkpoint inhibitors. Nevertheless, only a fraction of solid tumors responds to this immunotherapy modality. Another modality of immunotherapy consists of employing cell-based therapy as an adoptive therapeutic modality.

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Background: Low back pain (LBP) is the leading cause of disability worldwide, and the burden of LBP is expected to increase in coming decades, particularly in middle-income countries. There is a lack of large and high-quality studies investigating the prevalence of LBP in Brazil.

Objective: To estimate the point, one-year, and lifetime prevalence of non-specific LBP in adults from the city of São Paulo, Brazil.

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Photobiomodulation therapy (PBMT) has been used in several musculoskeletal disorders to reduce pain, inflammation, and promoting tissue regeneration. The current evidence about the effects of PBMT on low back pain (LBP) is still conflicting. We aimed to evaluate the effects of PBMT against placebo on pain intensity and disability in patients with chronic nonspecific LBP.

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