Comparative Effects of Vitamin D Supplementation on Oxidative Stress in Relapsing-Remitting Multiple Sclerosis.

Studies suggest that vitamin D (VitD) may reduce oxidative stress (OS) in multiple sclerosis (MS) patients. This study aimed to compare the effects of various VitD doses on OS in relapsing-remitting MS (RRMS). A 6-month supplementation was introduced using two doses of VitD: 2000 IU/day in the high-dose group (HD, = 23) and 15,960 IU/month in the low-dose group (LD, = 29).

Comparison of Methods for Short-Segment Posterior Stabilization of Lumbar Spine Fractures and Thoracolumbar Junction.

: Thoracolumbar and lumbar spine injuries account for 30-60% of spinal fractures, especially at the thoracolumbar junction. Conservative treatment is recommended for stable fractures without neurological symptoms, but studies suggest surgical intervention may offer better outcomes. However, there is no consensus on the best stabilization method.

Meta-Analysis of the Impact of Low-Dose Ionizing Radiation on Mortality and Progression of Heart Disease in the General Patient Population: Insights from Hormesis Theory in Cardiology.

Low-dose ionizing radiation (LDIR) is commonly used in medical diagnoses and certain professions, but its long-term effects on noncancer diseases, particularly cardiovascular disease (CVD), remain uncertain. While LDIR has recognized diagnostic benefits, its influence on CVD mortality and disease progression is still debated, with some suggesting that low doses may even have beneficial effects, as per the hormesis theory. This meta-analysis aimed to evaluate the impact of LDIR on cardiovascular health outcomes.

Serum Vitamin D3 as a Potential Biomarker for Neuronal Damage in Smoldering Multiple Sclerosis.

Permanent inflammatory demyelinating and neurodegenerative processes lead to neurological disability in patients with multiple sclerosis (MS). The anti-inflammatory properties of vitamin D (VitD) are well established, but its role in neurodegeneration is still uncertain. The usefulness of the serum concentration of VitD as a potential biomarker in evaluating brain injury in terms of recently known smoldering MS was under consideration.