Environ Res
March 2025
This study presents the green synthesis of silver nanoparticles (AgNPs) using Caryota urens leaf extract, emphasizing its role as a reducing and stabilizing agent. The synthesized AgNPs, characterized by UV-vis spectroscopy, FTIR, XRD, and SEM, were predominantly spherical, ranging from 10 to 50 nm. Biochemical assays revealed that bioactive molecules like flavonoids and phenolics contributed significantly to the formation and stability of AgNPs.
View Article and Find Full Text PDFAdenosine, a pervasive signaling molecule mediated by its interaction with G-protein-coupled receptor subtypes, especially the A adenosine receptor (AAR), plays a crucial role in cancer treatment. Recently, AAR targeting adenosine analogs have been proposed as a potential therapeutic target for cancer treatment. However, the molecules targeting AAR and their mode of action in inhibiting glioblastoma cell progression remain unknown.
View Article and Find Full Text PDFObjectives: This study aimed to evaluate the osseointegration properties of titanium bone implants coated with carob-mediated calcium hydroxide nanoparticles biomechanically, radiographically, and histologically on rabbit tibias.
Material And Methods: Forty coated and forty uncoated titanium alloy bone implants were inserted into 20 New Zealand rabbits; each tibia received 2 implants. The rabbits were sacrificed after 4 or 8 weeks, and samples were retrieved for biomechanical evaluation through removal torque test to assess the bond between implant and bone, radiographic evaluation through microcomputed tomography analysis to compare the bone-to-implant contact percentage and bone volume of the peri-implant area, scanning electron microscopic and histologic evaluation through hematoxylin and eosin stain.