The effects of phentolamine on the concentrations of TSH and the thyroid hormones in hemithyreoidectomized (hemiTXized) rats have been examined. Phentolamine caused a decrease of TSH level in blood serum 30 min after the injection, suggesting an inhibiting effect of phentolamine on TSH secretion. Thyroxine (T4) concentration decreased after 30 min.
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