Publications by authors named "M Rustico"
Background: The prognostic relevance of fetal/early postnatal magnetic resonance (MR) imaging (MRI) isolated "minor" lesions in congenital cytomegalovirus (CMV) infection is still unclear, because of the heterogeneity of previously reported case series. The aim of this study was to report the imaging and long-term clinical follow-up data on a relatively large cohort of infected fetuses.
Methods: Among 140 CMV-infected fetuses from a single-center 12-year-long fetal MRI database, cases that showed isolated "minor" lesions at MRI, mainly represented by polar temporal lesions, were selected.
Objective: First, to evaluate the risks of stillbirth and neonatal death by gestational age in twin pregnancies with different levels of growth discordance and in relation to small for gestational age (SGA), and on this basis to establish optimal gestational ages for delivery. Second, to compare these optimal gestational ages with previously established optimal delivery timing for twin pregnancies not complicated by fetal growth restriction, which, in a previous individual patient meta-analysis, was calculated at 37 0/7 weeks of gestation for dichorionic pregnancies and 36 0/7 weeks for monochorionic pregnancies.
Data Sources: A search of MEDLINE, EMBASE, ClinicalTrials.
Data about the neurological prognosis of isolated cerebellar hypoplasia in utero are scant and inconsistent. In this monocentric retrospective study, we describe the neurodevelopmental outcomes in a series of children with isolated cerebellar hypoplasia of presumably hemorrhagic origin prenatally detected with fetal magnetic resonance imaging (fMRI). We retrospectively reviewed the charts of all the pregnant women who were referred for a neurological consultation, diagnosed with fetal encephalic malformation/disruption between 2010 and 2020 in the Fetal Therapy Unit of our institution.
View Article and Find Full Text PDFArticle Synopsis
- The study examines right ventricular outflow tract abnormalities (RVOTA) in monochorionic/diamniotic (MC/DA) twin pregnancies that do not have twin-to-twin transfusion syndrome (TTTS).
- Among 891 MC/DA twin pregnancies analyzed from 2009 to 2018, RVOTA was found in 14 cases (1.6%), with pulmonary stenosis being the most common issue, often accompanied by other complications like amniotic fluid discrepancy and selective fetal growth restriction.
- The findings suggest that RVOTA can indeed arise in these pregnancies, and it highlights the need for specialized fetal echocardiographic evaluations and delivery in advanced care centers for affected cases.