Recently, there has been a growing interest in developing food-grade (F-G) microemulsions (MEMs) with potential applications in the food industry, such as a green solvent for extracting bioactive compounds or as a vehicle to solubilize low-polar bioactive compounds. Therefore, this work aimed to create F-G MEMs using a low-energy titration method, bile salt or tween 80 as surfactants, and F-G ingredients like acetic acid, olive oil, limonene, and coconut oil. For this purpose, 56 formulations were assessed, from which 14 created oil-in-water (O/W) one-phase Winsor type IV microemulsions.
View Article and Find Full Text PDFObjective: Atraumatic cerebrospinal fluid (CSF) rhinorrhea is uncommon in children and necessitates a multi-disciplinary evaluation for an etiology. Underlying osseous abnormality due to extensive or multifocal low flow vascular anomaly should be considered as a potential cause of spontaneous CSF leak. Treatment of multifocal low flow vascular anomalies may include medical and surgical approaches.
View Article and Find Full Text PDFKaposiform lymphangiomatosis is an uncommon generalized lymphatic anomaly with distinctive clinical, radiologic, histopathologic, and molecular findings. Herein, we document the pathology in 43 patients evaluated by the Boston Children's Hospital Vascular Anomalies Center from 1999 to 2020. The most frequent presentations were respiratory difficulty, hemostatic abnormalities, and a soft tissue mass.
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