Publications by authors named "M Ruiz-Castell"

Article Synopsis
  • The α-Gal syndrome (AGS) is linked to specific IgE antibodies against the carbohydrate galactose-α-1,3-galactose, primarily influenced by tick bites in those exposed to them, like forestry workers in Luxembourg.
  • A study analyzed blood samples and questionnaires from 219 forestry employees to determine their IgG and IgE responses to α-Gal compared to other groups, including food-allergic patients.
  • Results showed that 21% of forestry employees were sensitized to α-Gal, but both sensitized and non-sensitized exhibited high IgG levels, suggesting that tick bites promote strong immune responses, especially in AGS patients who had the highest IgG levels overall.
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Background: A substantial proportion of individuals continue experiencing persistent symptoms following the acute stage of their Covid-19 illness. However, there is a shortage of population-based studies on Long Covid risk factors.

Objective: To estimate the prevalence of Long Covid in the population of middle-aged and older Europeans having contracted Covid-19 and to assess the role of multimorbidity and socio-economic characteristics as potential risk factors of Long Covid.

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Purpose: The increased burden of multimorbidity is restricting individuals' ability to live autonomously, leading to a poorer quality of life. This study estimated trajectories of functional limitation and quality of life among middle-aged (ages 50 to 64 years) and older (aged 65 years and older) individuals with and without multimorbidity. We also assessed differences in the relationship between these two trajectories by multimorbidity status and separately for each age cohort.

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Background: Even though the prevalence of allergies is increasing, population-based data are still scarce. As a read-out for chronic inflammatory information, new methods are needed to integrate individual biological measurements and lifestyle parameters to mitigate the consequences and costs of allergic burden for society.

Methods: More than 480.

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Article Synopsis
  • The study investigated the adult exposome, focusing on chronic chemical exposures detected in hair samples of 442 participants from the European Health Examination Survey.
  • It identified 29 chemical pollutants present in over 70% of hair samples, revealing gender differences in exposure levels, particularly in pesticides and micronutrients.
  • The analysis highlighted low median correlations between diverse chemical exposures, with the highest correlations found within specific exposure groups, suggesting that hair analysis is a valuable method for future exposome research.
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