Publications by authors named "M Ruiz-Canela"

Background: Type 2 diabetes (T2D) has become a worldwide pandemic. While ceramides may serve as intermediary between obesity-related lipotoxicity and T2D, the relationship with simple glycosphingolipids remains uncertain. The aim of this study was to characterize the associations between blood glycosphingolipid and ceramide species with T2D and to identify a circulating sphingolipid profile that could serve as novel biomarker for T2D risk.

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Background And Aims: Moderate wine consumption has been associated with lower cardiovascular disease (CVD) risk in older populations. However, wine consumption information through self-reports is prone to measurement errors inherent to subjective assessments. The aim of this study was to evaluate the association between urinary tartaric acid, an objective biomarker of wine consumption, and the rate of a composite clinical CVD event.

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Impulsivity is an important determinant of human behaviour, affecting self-control, reasonable thinking and food choices. Recent evidence suggests a role for gut microbiota in human behaviour, but the relationship between gut microbiota and impulsive behaviours remains largely unexplored. To address this knowledge gap, the present study aims to explore the associations between faecal microbiota composition with trait and behavioural impulsivity, in a subcohort of the PREDIMED-Plus trial, including older adults presenting overweight/obesity.

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Article Synopsis
  • - Recent research in nutrition omics has significantly advanced our understanding of cardiovascular disease epidemiology and prevention, particularly through the findings of the PREDIMED trial, which linked specific diet-related metabolites to cardiovascular health.
  • - Key metabolites associated with cardiovascular disease and type 2 diabetes include ceramides, acyl-carnitines, branched-chain amino acids, tryptophan, urea cycle byproducts, and various lipids.
  • - Future research aims to create detailed metabolomic scores for better risk prediction, include diverse populations with varied dietary habits, and focus on practical applications of precision nutrition in clinical settings.
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Article Synopsis
  • The study looked at how a cooking program could help families eat more plant-based foods while following the Mediterranean diet.
  • The program included four cooking workshops led by a chef and a nutrition expert, and it aimed to improve cooking skills and nutrition knowledge for parents and kids.
  • Results showed that most families liked the workshops, parents got better at following the Mediterranean diet, and children ate more vegetables and less junk food.
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